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Studies have shown that women who take Paxil during certain times in their pregnancy are more likely to give birth to babies experiencing Paxil adverse effects than women who take other anti depressants or women who do not take any antidepressants during pregnancy. These side effects can be life-threatening and include serious health problems such as heart defects. At present, some women are investigating filing their own Paxil lawsuit, alleging the company didn’t properly warn them about the risks associated with taking the antidepressant during pregnancy.
In the studies made by the FDA, the risk of heart defects is about 1% overall and rose to 1.5 to 2 % in infants born to women taking Paxil. As a consequence of these studies, FDA and GlaxoSmithKline reclassified Paxil as “ Category D” drug for pregnant women. This means that studies shown that drug poses risk to pregnant women. Researchers have been concerned about selective serotonin reuptake inhibitors- Paxil is in this category—on fetuses for some time, but the FDA's announcement now indicates significant risk, particularly since a large number of pregnant women suffer from depression and are readily prescribed antidepressants, including Paxil.
A study from Sweden found that birth defects were twice as common among Paxil users as among women taking other antidepressants or none at all, and that most birth defects involve malformations in the chambers of the heart and holes. The defects often heal on their own but more severe cases must be surgically corrected.
Since Paxil was approved in 1993, it has become one of the world's most popular antidepressants, taken by tens of millions of patients and according to GlaxoSmithKline, about 25 percent of Paxil users are women of childbearing age, between 18 and 45.